Integrity of Primary Containers

Innovative First-Opening Indication for Prefilled Syringes from Schreiner MediPharm

A new tamper-evident security concept for luer-lock syringes has been developed by labeling specialist Schreiner MediPharm: Cap-Lock features a combination of a cap adapter and label that firmly seals prefilled syringes and reliably indicates any first opening. This ensures the integrity of the primary container and prevents any undetected opening of the cap.

Cap-Lock is a specially constructed plastic cap adapter that is precisely placed on top of the primary closure of the syringe to equalize the diameter differences of the syringe body and closure. Subsequently, a label with an integrated perforation for tamper evidence is applied that wraps around the syringe body and the bottom part of the cap adapter. When a user opens the syringe cap the label is partially destroyed, thus clearly and irreversibly indicating that the cap has been opened. This enables the user to quickly and intuitively tell if the medicine has been tampered with. Thus, patients are protected against administration of potentially counterfeit substances.

The utilization of Cap-Lock in daily healthcare settings is particularly easy, intuitive and safe: The syringe can be opened as usual and, due to the larger diameter, the adapter is easier to twist off even with gloves.

Cap-Lock from Schreiner MediPharm can be applied to the syringe in the conventional production process. Compared to shrink-wrap solutions, no heat is applied so that this solution is also suitable for sensitive substances. The label can be provided with additional functionalities such as counterfeit-proof features, detachable documentation labels or light protection. Both the label and adapter can be customized in terms of color and design. Due to the combination of the adapter with the primary closure of the syringe, no additional waste is generated because both parts are firmly connected to each other. The solution is adaptable to many commonly used syringe sizes.

At “PDA Universe of Pre-filled Syringes and Injection Devices 2019” in Gothenburg/Sweden in October, Schreiner MediPharm will present the newly developed Cap-Lock to an expert audience for the first time.

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Cap-Lock
Cap-Lock from Schreiner MediPharm easily, intuitively and safely protects syringes against undetected tampering attempts.

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About Schreiner MediPharm

Schreiner MediPharm, a business unit of Schreiner Group GmbH & Co. KG based in Oberschleissheim near Munich, is a leading developer and manufacturer of innovative, multifunctional specialty labels and marking solutions with value-added benefits for the healthcare industry. Thanks to its strong solutions expertise and specialized know-how Schreiner MediPharm is a highly capable development partner and reliable quality supplier to leading pharmaceutical and medical device technology companies worldwide.

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Bernd Pfadler
Product Communications

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